Are all QB notifications "No-Reply" emails

You can configure the single record notifications to come from a field on the record or a fixed user. But it must be a single record change type notification. 

Mark,

Thank you as always for your response. Congratulations on your well-deserved recognition at Empower24.  I need to clarify my question.  I am looking to determine if the recipient of any (no matter the [Sender Address]) notifications from QuickBase can reply directly to any Sender address in a QB email.  OR are all emails sent from Quickbase always unable to be directly responded to (no-reply).

Thanks again, Mark