Ability to have multiple calculated columns in reports

You can always concatenate several fields together to display in the custom column

var Text cellA = Upper(Left([FieldA], 1)) & Lower(NotLeft([FieldA], 1));
var Text cellB = ToText(2 * [FieldB]); 
$cellA & ", " & $cellB

Unfortunately you can use a Rich Text Formula field as a custom column so you can't synthesize HTML.